With the rise of GLP-1 medications, I’ve been interested in learning more about GLP-1 hormones and the role they naturally play in our bodies. I was excited to come across Let Your Body Do the Work by Anette Sams. Sams has a PhD, is a drug research specialist and is a former director at Novo Nordisk, the company behind Wegovy. Knowing this, I was prepared to read the book with a critical eye.
Sams doesn’t set out to promote GLP-1 medications, but neither does she suggest that people shouldn’t use them. Instead, her focus is on helping readers understand the body’s natural processes and the ways that food and lifestyle can support them. Throughout the book, she emphasizes that health isn’t black and white and that we each have a role to play in making choices about our own health.
This is a fairly short and easy-to-read book. There are some technical sections, but Sams does a good job of breaking down the information and explaining it in a way that is accessible to the general reader. The book also includes many illustrations, which I found particularly helpful as I am a visual learner.
Sams provides a helpful overview of the digestive system and the many processes involved in digestion, appetite, and metabolism before delving into GLP-1 and how it works in the body. She then explores how food and lifestyle can influence our natural GLP-1 response. Fibre, protein, healthy fats, physical activity, sleep and the gut microbiome all come into the discussion. I particularly appreciated the attention given to fibre and the gut microbiome. Rather than viewing GLP-1 solely through the lens of weight loss, Sams explains how this hormone is involved in appetite regulation, digestion and blood sugar control, giving readers a broader understanding of why GLP-1 has become such an important area of research.
I also particularly enjoyed the section on brown fat, or brown adipose tissue (BAT). I found this fascinating and appreciated learning about an aspect of metabolism that isn’t often discussed in mainstream nutrition conversations.
Many of the dietary principles Sams discusses will be familiar to anyone following a whole-food, plant-based approach: eating plenty of vegetables, fruits, legumes and other fibre-rich foods while emphasizing minimally processed foods. I found it interesting to see these familiar principles discussed through the lens of GLP-1 and appetite regulation.
Overall, I found Let Your Body Do the Work an interesting and informative read, and I appreciated the compassion and understanding that comes through in Sams’ writing. For anyone interested in learning more about GLP-1 and how our bodies regulate appetite and metabolism, this is an accessible place to start.
And I especially loved the final paragraph of the book:
“My wish for you is a long and healthy life with all the freedom to make your own choices. And lots of vegetables! Always lots of vegetables.”
Now that’s something I can cheer!